Linear IgA disease ES111 (LAD) is a rare autoimmune bullous disease characterized by IgA deposition in the basement membrane zone (BMZ).A 66-year-old male was treated for myelodysplastic syndrome at our hospital for 5 years, during which his condition remained stable.He visited our department because of erythema with itching, which appeared 1 year
This study provides a novel methodology for the natural frequency estimation of the jet engine turbine blade by using the dimension check.This paper presents a summarization of the ongoing research devoted to the method for the turbine blade natural frequency estimation.The main target of the research presented in the paper is to develop a novel me
Ligand-targeted toxins (LTTs) are bioengineered molecules which are composed of a targeting component linked to a toxin that induces cell death once the LTT binds its target.Bispecific targeting allows for the simultaneous targeting ES111 of two receptors.In this review, we mostly focus on the epidermal growth factor receptor (EGFR) as a target.We
To effectively nurture the talents of elementary students with mathematical talent they need to be challenged with an advanced curriculum that is designed with their specific needs in mind.The purpose of this paper is to describe an effective model for developing such a curriculum and explore effective, research-based examples of curriculum and ins
Spatial competition plays important roles in economics, which Sticky Notes attracts extensive research.This paper addresses spatial competitions along with horizontal product differentiations and entry deterrence.By the dynamic game theory model about one firm and a potential entrant with different cost in a linear city, this paper finds that both